The Rise of Biocatalysis

Most chemists think of biocatalysis in terms of ester hydrolysis or perhaps asymmetric reduction. But modern biocatalysts can do unusual transformations including remote oxidations and stereoselective carbon-carbon bond formations, as the examples below, taken from the recent literature, demonstrate.

JACS 2006, 128, 6058 (gropups of Backvall and Arnold) Work at DSM and RCAB Graz, Angew Chem Int. Ed, 2006, 45, 3454

 

C Qiao etc al, JACS, 2005, 127, 8608


Trevor Laird