Issue 37 February/March 2011
What's New in Process Chemistry?
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Newsletter Issue 37 February/March 2011.
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| β-Alkylation of Alcohols |
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Dr John Knight
I noted with interest the paper by Allen and Crabtree (Green Chem, 2010, 12, 1362) wherein they describe the formation of a C-C bond between a secondary and a primary alcohol without transition metal catalysis.
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| Carboamination |
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Dr John Knight
Whilst there are many methods for making C-N bonds such as displacement of a leaving group and reductive amination of course, the introduction of additional enantioselective methods are always of interest.
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| Quantitative HPLC Analysis for Chemists – Open Access |
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Dr John Knight
During early phases of chemical development it can be difficult to get a good handle on the performance of reactions and processes in the absence of developed analytical methods.
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| Ester and Amide Reduction with DEANB Complex |
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Dr Will Watson
Esters and amides can be reduced by N,N-diethylaniline:borane complex in the presence of SpiroCAT.
Aliphatic esters are reduced at room temperature whilst aromatic esters require higher temperatures, 50°C, and longer reaction times.
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| Have you read our Blogs? |
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Moving into a new Chemistry Year - indeed new decade! - our resident experts, Drs John Knight and Will Watson have both submitted Blog articles: John reflects on the last year and what we might expect for this, in 'Chemistry Year Reflections' and Will poses the question 'What are the Top 10 Organic Reactions?'
We'd love your comments!
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| ... and finally - you might be an engineer if...... |
| ... you sit backwards on the Disneyland rides to see how they do the special effects. |
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Dates for your diary...
Click to view our 2011 Conference and Course Dates
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CONFERENCES
Organic Process Research & Development
28 February - 2 March
Clearwater Beach, FL, USA
Modern Synthetic Methods and Chiral Europe
23 - 25 May 2011
Edinburgh, Scotland
COURSES
Understanding Polymorphism & Crystallisation Issues in the Pharmaceutical Industry
1 - 3 March 2011
Barcelona, Spain
Secrets of Batch Process Scale-Up
9 - 11 March 2011
Lisbon, Portugal
Interfacing Chemistry with Patents
15 - 16 March 2011
Barcelona, Spain
Scaling from Milligrams to Kgs
17 - 18 March 2011
Basel, Switzerland
Medicinal Chemistry
22 - 24 March 2011
London, UK
Chemical Development & Scale-Up in the Fine Chemical & Pharmaceutical Industries
5 - 7 April 2011
Nice, France
Stretch your training budget - register 2 or more delegates and SAVE up to 15%!
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Don't Forget
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Explore the benefits of networking at one of our prestigious events with video from one of last year's conferences.
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