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Process Chemistry News

Challenges to Find Commercially Viable Routes to Agrochemicals

Written by Dr Will Watson on Wednesday, 11 February 2015. Posted in Process Chemistry News

Dr Roland Goetz (BASF) gave a presentation, during the 'Organic Process R & D' Conference in Pune in December which highlighted the challenges faced in trying to identify commercially viable routes to agrochemicals, which are typically low cost products that still contain a significant degree of complexity. One point he made was that companies have to re-register products every 10 years and as a result about 70% of old active ingredients have been withdrawn, mainly due to their negative impact on the environment.

Roland Scheme


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The First 10 Lessons Learned in DoE

on Tuesday, 10 February 2015. Posted in Process Chemistry News

Today Quality by Design (QbD) is implemented primarily for economic considerations, and less because of possible regulatory flexibility that could be gained. The value added by QbD methodology has two components:
(i) very low cost of poor quality, and
(ii) systematically generated process understanding
(as Dr. Thien from Merck recently commented about the role of chemical process R&D: "...we make material ....and we make knowledge...").


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Scientific Update, established in 1989 by Dr. Trevor Laird, organises conferences and training courses for industrial chemists and chemical engineers in chemical development and scale-up and many other specialist topics in organic chemistry. We also provide extensive consultancy services in these fields and edit the international scientific journal entitled Organic Process Research and Development (OPRD).

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