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Scientific Update, established in 1989 by Dr. Trevor Laird, organises conferences and training courses for industrial chemists and chemical engineers in chemical development and scale-up and many other specialist topics in organic chemistry. We also provide extensive consultancy services in these fields and edit the international scientific journal entitled Organic Process Research and Development (OPRD).

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Scientific Update - We've Got Chemistry!

20 January 2012

Green Chemistry

Written by Dr Will Watson

How do the fine chemical, pharmaceutical, and related industries approach green chemistry and sustainability?

Recently published in the RSC Journal - Green Chemistry

William J. W. Watson

Green Chem., 2012, Advance ArticleDOI: 10.1039/C1GC15904F

 

Developing manufacturing processes for active pharmaceutical ingredients and intermediates often involves complex chemistry.

All companies now aim to uphold the principles of green chemistry and sustainability as far as possible, but how effective are they in achieving this and how much variation is there from company to company?

This perspective discusses the results of a survey carried out with 24 companies, including 11 “big pharma” companies and 6 “other pharma” companies. Companies from outside the pharma sector were also included to give a comparison with other areas of the fine chemical industry. These included two fine chemical manufacturers, one agrochemical manufacturer, and one flavour and fragrance company.

The survey covered organisational aspects of green chemistry and sustainability, such as corporate policy and policy implementation, green chemistry and technologies, process metrics, and how the application of green issues changes through the various stages of development and whether there are different standards for low volume and/or high potency compounds.

About the Author

Dr Will Watson

Will Watson gained his PhD in Organic Chemistry from the University of Leeds in 1980. He joined the BP Research Centre at Sunbury-on-Thames and spent five and a half years working as a research chemist on a variety of topics including catalytic dewaxing, residue upgrading, synthesis of novel oxygenates for use as gasoline supplements, surfactants for use as gasoline detergent additives and non-linear optical compounds. In 1986 he joined Lancaster Synthesis and during the next 7 years he was responsible for laboratory scale production and process research and development to support Lancaster’s catalogue, semi-bulk and custom synthesis businesses. In 1993 he was appointed to the position of Technical Director, responsible for all Production (Laboratory and Pilot Plant scale), Process Research and Development, Engineering and Quality Control. He helped set up and run the Lancaster Laboratories near Chennai, India and had technical responsibility for the former PCR laboratories at Gainesville, Florida. He joined Scientific Update as Technical Director in May 2000. He is also involved in an advisory capacity in setting up conferences and in the running of the events. He is active in the consultancy side of the business and sits on the Scientific Advisory Boards of various companies.

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