Alkyl hydrazines made simple

21 March 2005

Kevin Meyer at Dow (USA) has reported* a simple, robust two step process for the preparation of monoalkylhydrazines, using inexpensive and readily accessible t-butyl carbazate acetone hydrazone as the hydrazine source.

Yields are good, and even propargyl bromide (usually problematic) can be used.

* K.G. Meyer, SYNLETT, 2004, (13), 2355-2356.