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Conglomerates - More Common than you Think

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27 February 2004

Conglomerates are usually much easier to work with than racemates and can be resolved without the use of a resolving agent. The prevalence of conglomerates (mechanical mixtures of enantiomers) is reckoned to be between 1 in 10 and 1 in 15 of all known compounds. However when salts are examined, conglomerates are much more common, with 20% of salts being conglomerates. This means that you should only need to examine 5 salts before finding a conglomerate (from Optical Resolutions, Theory & Practice, Scientific Update Training course given by D. Kozma and K. Marthi, Nov 2003).