The Design, Development and Scale-Up of Safe Chemical Processes and Operations
10 - 12 June 2008, Southampton, UK
A 3 day course for chemists and engineers given by

Developing safe processes is of paramount importance to any chemical company. Exothermic chemical reactions in batch and semi- batch processes can result in serious injury to people and plant if they get out of control. Results of thermal runaways include violent loss of containment, possibly explosion and the release of flammable or toxic materials to the environment. There are around 30 such incidents reported in the UK each year, and many more “near misses” go unreported. The costs associated with an incident can be very high.
Employers are bound by Health & Safety legislation to ensure the safety of their employees and those outside their employment who might he affected by their activities. Chemical manufacturers must therefore be aware of all potential dangers in their processes and take steps to eliminate them. The best approach is to design safety into the process from the start.
Often, the first sign of loss of control over a reaction is a reduction in yield or in the quality of the product. Thus safety, quality and profitability are all interlinked.
This course is designed to enhance the awareness of chemists and engineers regarding hazard issues. Utilizing the expertise of the chemists and chemical engineers at Scientific Update and Chilworth Technology, it will consider hazard control of new chemical processes throughout their development cycle: from early development through to full-scale production. Hazards can often be eliminated by appropriate choice of reagent or synthetic route at the R&D stage. Where this is not possible, techniques exist to quantify the hazards so that robust engineering solutions can he applied in production.
Course Objectives
- To train chemists and engineers in efficient methods for developing safe, low cost, robust processes for the manufacturer of fine organic chemicals in the minimum amount of time.
- To improve the awareness of chemists on the principles of scale-up and development, in chemical engineering concepts relating to safe plant operation and in the latest techniques for the optimisation processes.
- To learn from the experience (and mistakes) of others by examining case studies from industry
What You Leave With...
- The ability to identify any significant sources of hazard in existing processes or development plans.
- An understanding of the latest techniques for assessing risk, and measuring and quantifying chemical process hazards in the work place.
- An understanding of the established best practice to reduce the hazard resulting from exothermic reaction systems with a particular emphasis on emergency relief design
The organisers reserve the right to change the published programme of events and course content as circumstances dictate.
