Understanding Organic Reactions
The Key to Making Reactions Work
7 - 9 October 2008, Basel, Switzerland
A 3 day course given by
Dr Krister Zetterberg, Royal Institute of Technology, Stockholm, Sweden
For many synthetic chemists, physical chemistry is something they “left behind” at the end of their degree course. Indeed, in many degree courses, organic chemistry and physical chemistry were taught in relative isolation, and important links between the two were often not made. Clearly, if synthetic chemists are to control organic reactions to increase yield and rate of reaction, to minimize or eliminate byproducts, and to enhance chemo and stereoselectivity, they must understand more about thermodynamics and kinetics – the physical organic chemistry associated with the reaction.
This course is specifically designed to help graduate and PhD level synthetic chemists (including those with a phobia of physical chemistry!) revive their physical chemical knowledge and understanding in a way that will be of real practical use in their current role.
At the end of the course participants will have gained
- A rational approach to physical organic chemistry.
- A method to screen hypothetical reactions as reasonable or not and help in choice of reagents.
- A Simple way to discuss reactivity in terms of orbitals.
- An improved understanding of reactivity in organic chemistry.
- A set of concepts that helps to understand many of the observations presented in modern text-books concerning reversibility, heat of reaction, rate of reaction, rate of acceleration or deceleration due to hydrogen bonds, competing reactions.
- A limited collection of “rules of thumb” useful for organic chemists.
- A simple, qualitative method to estimate energetics in organic reactions.
- A slightly different, more mechanistic way to look at organic chemistry. i.e A more coherent view of organic chemistry
- Knowledge of some important facts that can not be found in text books, sophomore as well as advanced but should have appropriately been stated there!
The organisers reserve the right to change the published programme of events and course content as circumstances dictate.
