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Process Chemistry News

Comprehensive Review on Process Analytical Technology

Written by Dr Trevor Laird on Monday, 12 January 2015. Posted in Process Chemistry News

OPRD has just published as an ASAP article a long and very comprehensive multi-author review (with hundreds of up-to-date references) showing the state of the art in PAT. (Levente S; doi 10.1021/op500261y). It is particularly strong in crystallisation technologies and has some good industrial case studies. The review forms part of a special feature section devoted to PAT which will appear in the Jan 2015 edition of OPRD.

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Brainteaser

Written by Dr Will Watson on Monday, 12 January 2015. Posted in Process Chemistry News

Workers at Merck wanted to hydrolyse nitrile (20) to acid (2), so they chose to heat the nitrile in 5N HCl at 40°C.  They were somewhat surprised to obtain the desired acoid (2) contaminated with isomer (21) formed in up to 15% yield or a ratio of 89:11.

J.Y.L. Chung,* Y.-L. Zhong,* K.M. Maloney,* R.A. Reamer, J.C. Moore, H. Strotman, A. Kalinin, R. Feng, N.A. Strotman, B. Xiang, and N. Yasuda, Org. Lett., 2014, 16, 5890-5893.

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Process Chemistry Training & Conferences

Scientific Update, established in 1989 by Dr. Trevor Laird, organises conferences and training courses for industrial chemists and chemical engineers in chemical development and scale-up and many other specialist topics in organic chemistry. We also provide extensive consultancy services in these fields and edit the international scientific journal entitled Organic Process Research and Development (OPRD).

Our short intensive training courses enable scientists to learn about highly relevant topics, to broaden their knowledge and to keep abreast of new science, new technology and new techniques. A complete list of the scheduled training courses currently available can be viewed in the training section. Many of these are also available for in-house training.

Our specialist conferences provide the perfect forum for organic process chemists and chemical engineers to network with experts from industry and academia from all over the world.

Our aim is to provide you with the very best, up-to-date chemistry and superb locations. At every event, Scientific Update provide the highest quality organisation and friendly support from all our team.  We look forward to welcoming you to one of our events soon.

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